The Good, the Bad, and the Lethal: Gene Expression and Metabolomics Reveal Physiological Mechanisms Underlying Chronic Thermal Effects in Mayfly Larvae (Neocloeon triangulifer)
نویسندگان
چکیده
Citation: Chou H, Pathmasiri W, Deese-spruill J, Sumner SJ, Jima DD, Funk DH, Jackson JK, Sweeney BW and Buchwalter DB (2018) The Good, the Bad, and the Lethal: Gene Expression and Metabolomics Reveal Physiological Mechanisms Underlying Chronic Thermal Effects in Mayfly Larvae (Neocloeon triangulifer). Front. Ecol. Evol. 6:27. doi: 10.3389/fevo.2018.00027 The Good, the Bad, and the Lethal: Gene Expression and Metabolomics Reveal Physiological Mechanisms Underlying Chronic Thermal Effects in Mayfly Larvae (Neocloeon triangulifer)
منابع مشابه
Bioaccumulation Dynamics of Arsenate at the Base of Aquatic Food Webs.
Periphyton is an important food source at the base of freshwater ecosystems that tends to bioconcentrate trace elements making them trophically available. The potential for arsenic-a trace element of particular concern due to its widespread occurrence, toxicity, and carcinogenicity-to bioconcentrate in periphyton and thus be available to benthic grazers is less well characterized. To better und...
متن کاملEffects of doxepin on spatial memory, TNF-α and Bcl-2 family genes expression in rat hippocampus
Introduction: Although the initial hypothesis for the action of doxepin was based on the inhibition of the reuptake of neurotransmitters, it has been suggested that it may also involve other mechanisms. Therefore, this study aims to investigate the effect of doxepin on spatial memory, tumor necrosis factor alpha (TNF-&alpha) level, expression of pro-apoptotic (Bad and Bax) and anti-apoptotic (B...
متن کاملClassification of Chronic Kidney Disease Patients via k-important Neighbors in High Dimensional Metabolomics Dataset
Background: Chronic kidney disease (CKD), characterized by progressive loss of renal function, is becoming a growing problem in the general population. New analytical technologies such as “omics”-based approaches, including metabolomics, provide a useful platform for biomarker discovery and improvement of CKD management. In metabolomics studies, not only prediction accuracy is ...
متن کاملInvestigating the Lethal Effects of Lead Chloride (PbCl2) on Blood Indices, Liver Enzymes and Evaluation on Cytochrome P450 Gene Expression in Common Carp (Cyprinus carpio)
The aim of this study was to investigate the sub-lethal effects Lead Chloride (PbCl2) on blood indices, liver enzymes, cytochrome P450 gene expression in common carp. For this purpose, Fish with a mean weight of 7 33±0.33 g were prepared and divided into 3 treatments and a control group and exposed to effective concentrations (0.05, 0.15, 0.25 mg / l) of sublethal toxicity for a period of 14 da...
متن کاملMetabolomics analysis of the saliva in patients with chronic hepatitis B using nuclear magnetic resonance: a pilot study
Objective(s): Hepatitis B virus infection causes chronic disease such as cirrhosis and hepatocellular carcinoma. The metabolomics investigations have been demonstrated to be related to pathophysiologic mechanisms in many disorders such as hepatitis B infection. The aim of this study was to investigate the saliva metabolic profile of patients with chronic hepatitis B in...
متن کامل